一、基本信息
姓名:张凡
职称:副教授,硕士生导师,湖北省“楚天学子”
研究领域:纳米孔电分析和生物分子传感
电子邮件:fanzhang@hubu.edu.cn
二、教育背景及工作经历
2012.9—2018.6 华中师范大学,博士,分析化学
2018.7—2021.8 湖北大学 化学化工学院,讲师
2021.9—2022.10湖北大学 化学化工学院,副教授
2022.10—至今 湖北大学 健康科学与工程学院,副教授
三、研究方向
目前主要研究方向为:
1. 纳米孔电化学传感器的构建及疾病标志物检测应用;
2. 仿生亚纳米孔道的构建及膜分离性质研究。
主持国家自然科学基金项目1项,湖北省自然科学基金项目1项,以第一作者/通讯作者在Angew. Chem. Int. Ed. (2篇), Advanced Science, Chemical Science, Analytical Chemistry, Chemical Communications,Coordination Chemistry Reviews等学术刊物发表SCI论文30余篇。
四、科研项目
1. 国家自然科学基金青年项目, 21904031, 一氧化氮响应的纳米孔道分析平台设计、构建及细胞实时检测应用, 2020/01—2022/12,30万元, 主持,结题。
2. 湖北省科技厅自然科学基金, 青年项目, 2019CFB121, 仿生纳米孔道的设计构建及对肿瘤标志物检测应用, 2019/01—2020/12, 5万元, 主持,结题。
五、代表性论文
1. Lei Yang; Ming Cheng; Jiaxin Quan; Siyun Zhang; Lu Liu; Robert P. Johnson; Fan Zhang;(*) Haibing Li,(*) Construction of A High-Flux Protein Transport Channel Inspired by the Nuclear Pore Complex, Angewandte Chemie-International Edition, 2021, 60:24443-24449. (SCI一区, IF=16.823)
2. Zhiqiang Mao; Hyeonji Rha; Jungryun Kim; Xinru You; Fan Zhang; (*) Wei Tao; (*) Jong Seung Kim,(*)THQ-Xanthene: An Emerging Strategy to Create Next-Generation NIR-I/II Fluorophores, Advanced Science, 2023, 10, 2301177. (SCI 一区,IF=17.521)
3. Zhiqiang Mao; Ji Hyeon Kim; Jieun Lee; Hao Xiong; Fan Zhang; (*) Jong Seung Kim, (*) Engineering of BODIPY-based theranostics for cancer therapy, Coordination Chemistry Reviews 2023, 476, 214908. (SCI一区, IF=24.833)
4. Wenhui Liu; Weiwei Xu; Hang-Hang Luan; Guang Li; Junan Liu; (*) Zhiyan Lu; (*)Fan Zhang; (*) Haibing Li,(*) L-ribose specific recognition surface constructed by pillar[5]arene-based host–guest interaction, Biosensors and Bioelectronics, 2023, 241, 115678. (SCI一区, IF=12.545)
5. Xing Wang; Jing Wu; Rui Lv;Yurong Bai; Caixia Wang; Fan Zhang; (*) and Zhihong Liu(*), Bioinspired Hydrogen Peroxide-Activated Nanochannels and Their Applications in Cancer Cell Analysis. Analytical Chemistry, 2022, 94, 6234−6241. (SCI一区, IF=8.008)
6. Lei Ge; Jing Wu; Caixia Wang; Fan Zhang;(*) Zhihong Liu,(*) Engineering artificial switchable nanochannels for selective monitoring of nitric oxide release from living cells, Biosensors and Bioelectronics, 2020, 169:112606. (SCI一区, IF=12.545)
7. Jing Wu; Xing Wang; Lei Ge; Rui Lv; Fan Zhang;(*) Zhihong Liu,(*) Gold nanoparticle integrated artificial nanochannels for label-free detection of peroxynitrite, Chemical Communications, 2021, 57:3583-3586. (SCI二区, IF=6.065 )
8. Guang Li; Wen Gong; Lei Yang; Ming Cheng; Hewei Yan; Jiaxin Quan;(*) Fan Zhang; (*) Zhiyan Lu;(*)and Haibing Li,(*) Guest-Induced Planar-Chiral Pillar[5]arene Surface for Selectively Adsorbing Protein Based on Host−Guest Chemistry. Bioconjugate Chemistry, 2022, 33, 2237-2244. (SCI二区, IF= 6.069)
9. Fan Zhang; Yue Sun; Demei Tian; Haibing Li,(*) Chiral Selective Transport of Proteins by Cysteine-Enantiomer Modified Nanopores, Angewandte Chemie-International Edition, 2017, 56(25): 7186-7190. (SCI一区, IF=16.823)
10. Fan Zhang; Junkai Ma; Yue Sun; Imene Boussouar; Demei Tian; Haibing Li(*); Lei Jiang, Fabrication of a mercaptoacetic acid pillar[5]arene assembled nanochannel: a biomimetic gate for mercury poisoning, Chemical Science, 2016, 7 (5): 3227-3233. (SCI一区, IF=9.969 )
11. Fan Zhang; Junkai Ma; Yue Sun; Yuxiao Mei; Xue Chen; Wenqian Wang; Haibing Li,(*) Construction of a Switchable Nanochannel for Protein Transport via a Pillar[5]arene-Based Host-Guest System, Analytical Chemistry, 2018, 90 (13): 8270-8275. (SCI一区, IF=8.008)
12. Fan Zhang; Yue Sun; Demei Tian; Weon Sup Shin; Jong Seung Kim ;(*) Haibing Li,(*) Selective molecular recognition on calixarene-functionalized 3D surfaces, Chemical Communications, 2016, 52(86): 12685-12693. (SCI一区, IF=6.567 )