一、基本信息
曹宇,副教授,硕士生导师,省级人才
研究领域:纳米药物的研发与应用,脑胶质瘤的精准诊断与治疗
电子邮件:caoyu@hubu.edu.cn
二、教育背景及工作经历
2022.11至今,湖北大学,健康科学与工程学院,副教授
2020-11至2022-10,湖北大学,化学化工学院,副教授
2019-07至2020-10,湖北大学,化学化工学院,讲师
2014-09至2019-06,北京科技大学,化学与生物工程学院,博士
2010-09至2014-06,北京科技大学,化学与生物工程学院,学士
三、研究方向
纳米药物的研发与应用,脑胶质瘤的精准诊断与治疗
四、科研项目
1. 国家自然科学基金青年项目,仿生MXene基二维声敏剂的构建及其脑胶质瘤声动力学治疗应用研究,2023/01-2025/12,30万,主持,在研。
2. 湖北省自然科学基金面上类项目,响应型仿生纳米药物的构建及其在脑胶质瘤声动力学治疗中的应用, 2021/10-2023/09,8万,主持,在研。
五、代表性论文
1. Wu, T.; Liu, Y.; Cao, Y.*; Liu, Z.*, Engineering macrophage exosome disguised biodegradable nanoplatform for enhanced sonodynamic therapy of glioblastoma. Adv. Mater. 2022, e2110364.
2. Lu, H.; Guo, K.; Cao, Y.*; Yang, F.; Wang, D.; Dou, L.*; Liu, Y.*; Dong, H.*, Cancer cell membrane vesicle for multiplex microRNA imaging in living cells. Anal. Chem. 2020, 92, 1850-1855.
3. Cao, Y.; Wu, T.; Dai, W.; Dong, H.*; Zhang, X.*, TiO2 Nanosheets with the Au Nanocrystal-Decorated Edge for Mitochondria-Targeting Enhanced Sonodynamic Therapy. Chemistry of Materials 2019, 31 (21), 9105-9114.
4. Cao, Y.; Wu, T.; Zhang, K.; Meng, X.; Dai, W.; Wang, D.; Dong, H.*; Zhang, X.*, Engineered Exosome-Mediated Near-Infrared-II Region V2C Quantum Dot Delivery for Nucleus-Target Low-Temperature Photothermal Therapy. ACS Nano 2019, 13, 1499-510.
5. Cao, Y.; Li, S.; Chen, C.; Wang, D.; Wu, T.; Dong, H.*; Zhang, X.*, Rattle-type Au@Cu2-xS hollow mesoporous nanocrystals with enhanced photothermal efficiency for intracellular oncogenic microRNA detection and chemo-photothermal therapy. Biomaterials 2018, 158, 23-33.
6. Cao, Y.; Meng, X.; Wang, D.; Zhang, K.; Dai, W.; Dong, H.*; Zhang, X.*, Intelligent MnO2/Cu2-xS for Multimode Imaging Diagnostic and Advanced Single-Laser Irradiated Photothermal/Photodynamic Therapy. ACS Appl. Mater. Interfaces 2018, 10, 17732-17741.
7. Cao, Y.; Dong, H.*; Yang, Z.; Zhong, X.; Chen, Y.; Dai, W.; Zhang, X.*, Aptamer-Conjugated Graphene Quantum Dots/Porphyrin Derivative Theranostic Agent for Intracellular Cancer-Related MicroRNA Detection and Fluorescence-Guided Photothermal/Photodynamic Synergetic Therapy. ACS Appl. Mater. Interfaces 2017, 9, 159-166.
8. Cao, Y.; Dong, H.*; Pu, S.; Zhang, X.*, Photoluminescent two-dimensional SiC quantum dots for cellular imaging and transport. Nano Research 2018, 11, 4074-4081.